Nathaniel Thomas Lupton was born near Winchester, Virginia on Dec. 19th, l830, son of Daniel and Elizabeth Lupton.  He was graduated from Dickinson College at the young age of 18, and began to study law before finally devoting his time to the study of chemistry.  Lupton taught chemistry at several female colleges before accepting the chair of chemistry at Randolph-Macon College in l857, and was appointed to the same chair in l858 at   the new Southern University in Greensboro, Alabama.  The University was not opened until l859 and Lupton spent the intervening months studying chemistry under the famous Professor Bunsen in Heidelberg, Germany.  Lupton remained at Southern for 12 years, where he also worked as a chemist for the Confederate Nitre and Mining Bureau during the Civil War.  From l871 - 1874,  Lupton served as President of the University of Alabama, and in 1874 he accepted appointment as the professor of chemistry at Vanderbilt University in Nashville, Tennessee.  With twelve months leave between jobs, Lupton again went to Germany to study with Bunsen.

During his tenure at Vanderbilt, Lupton befriended a local dentist and entrepeneur, William H. Morgan, who would later come to occupy the chair of dentistry at Vanderbilt.   Morgan was a bear of a man, a devout Methodist, born into comparative poverty, with an honest pride to be the best at whatever he undertook.   In the late l870's, Morgan was President of the Santa Gertrudis Silver Mining Company, a Nashville firm which came to specialize in speculation of mines in Mexico.   In May of 1879 Morgan hired Lupton to assay ore at a silver mine near Santa Rosa in Coahuila, Mexico.

Mexico in the late l870's and l880's sustained a "silver rush" of sorts from American mining companies, with speculators seeking to become rich from formerly inaccessible ore deposits in the old mines of Mexico.  Many of the older Mexican mines had become flooded with groundwater, and American technology, particularly pumps designed to remove water from mining shafts, was thought to be the savior.  Lupton's job was to assay ores and ascertain if it was economically feasible to exploit certain mines or veins.

Lupton's first foray into Mexico may have been in l878, for the l878-79 Register of Vanderbilt University lists a gift from Lupton to the school museum of "silver ore" from the Mexican state of Chihuahua.   In the 1879-80 volume, the Register reported another donation of "silver ore" from  Lupton, this one from Coahuila.  On June 8th of the same year, the Nashville Daily American reported that Morgan and Lupton were leaving the next day for Mexico (via El Paso) to visit the Santa Gertrudis mines in Coahuila.  Travel at the time was slow and difficult, and there were no passenger trains in southwest Texas nor in northern Chihuahua or Coahuila.  Thus connections south and west of San Antonio were by stagecoach.  Why  Lupton was first going to El Paso is unknown.  El Paso was about 7 days  west of San Antonio via stagecoach in l879, and the route to the Santa Gertrudis mines was through  Eagle Pass, which was about 36 hours due south via stage from San Antonio.  Perhaps Lupton and Morgan traveled to El Paso to examine some mines in New Mexico. In any event, to reach Santa Gertrudis in Coahuila  they would have backtracked to enter Mexico via Eagle Pass.   They did reach Coahuila in l879, as Lupton  published a short article in 1880 about meteoric iron from Coahuila, noting that he viewed the meteorite in Santa Rosa, Coahuila, about 120 miles south of Eagle Pass, Texas, "while on a visit to Mexico in July, l879."  Santa Rosa was the largest town of any consequence near the Santa Gertrudis mine.

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